An episode of The Powerpuff Girls opens with the Gangrene Gang raiding a convenience store. Snake is drinking slushies straight from the machine. He screams in pain as he gets a brain freeze...then dives straight back in. When the gang gets superpowers, his end up being cryokinesis.
In Phineas and Ferb The Movie: Across the 2nd Dimension, feature-length film, one of Perry's special weapons will give the victim an ice cream headache.